Institute for Aging Research
1200 Centre Street
Boston, MA 02131
OVERVIEW OF CURRENT ROLE
Wen-Chi Chou is a Post-Doctoral Research Fellow for Institute for Aging Research’s (IFAR) Musculoskeletal Research Center at Hebrew SeniorLife and at Harvard Medical School. Trained as a computational biologist, Dr. Chou conducts genetic research to further the understanding of bone diseases such as osteoporosis and fractures. His research heavily involves computational and statistical approaches with high-throughput and big data.
HISTORY AT IFAR AND EXAMPLES OF RESEARCH
Dr. Chou joined IFAR in September 2012. After joining the team, he extended a genetic research study led by Dr. Douglas P. Kiel and Dr. Yi-Hsiang Hsu; and identified more genetic variants that may lead to losses and gains of bone mineral density. His research data came from many cohorts in different countries, and thus his work would be able to explain the relationship between genetic variants and disease phenotypes universally but not limited in some populations.
Dr. Chou received his B.S. in Medical Technology in 2000 and obtained a Masters degree in Molecular Biology in 2002. From 2002 until 2007, he was employed by the Institute of Information Science, Academia Sinica as a Research Assistant and began work on bioinformatics studies such as biomedical text mining. Dr. Chou obtained a Ph.D. in Bioinformatics from the University of Georgia in 2012 and was then recruited to IFAR as post-doctoral research fellow by Dr. Kiel and Dr. Hsu. In 2011 he worked as a Research Intern at Eli Lilly and conducted genomic studies of liver cancer. Dr. Chou currently serves as a co-investigator on grant proposals.
CONTRIBUTIONS/ FUTURE DIRECTIONS
Dr. Chou has published 20 research papers and also serves as an ad hoc reviewer for journals such as Bioinformatics, Nucleic Acid Research and PLoS ONE.
Dr. Chou intends to use his multidisciplinary knowledge and skills to answer the relationship between genetics and bone diseases. Specifically, he is seeking the best approach to build models for fundamental mechanisms of bone diseases. He is also pursuing funding opportunities to support his research goals.